Entitled “Just Say Hello”, the video campaign – organised by talk show queen Oprah Winfrey – encourages people to reach out to others.
Julia appears alongside a host of stars, including Taylor Swift, Jennifer Aniston, Ellen DeGeneres and Tom Hanks, in the clip.
It was a fairly easy job as far as acting goes, with Julia only having to say two words: “Hi babe!”
The timing of the campaign’s release was poignant for Julia – it occurred on the same day her half-sister Nancy Motes’ death certificate was released. Nancy was found dead of a suspected drug overdose in her Santa Monica apartment on February 9.
In the weeks before her death, she’d tweeted several messages about Julia, accusing her of abandoning her.
It’s been a tough start to the year for Julia – she revealed this week that her mother is suffering from lung cancer.